Owen Farrell will captain England against Argentina on Sunday with Alex Coles making his Test debut.
With Courtney Lawes absent, Farrell skippers Eddie Jones’ team once again with Northampton second-row Coles earning his first Test cap in the pack.
The match is England’s first of four this autumn, and despite the team battling a host of injuries, Jones is able to pick Manu Tuilagi at outside centre alongside Farrell, with Marcus Smith at fly-half and Ben Youngs in at No.9. Freddie Steward, Jack Nowell and Joe Cokanasiga form the back three.
In the pack Ellis Genge, Luke Cowan-Dickie and Kyle Sinckler form the front-row with Coles partnering Jonny Hill in the second-row. Maro Itoje, Tom Curry and Billy Vunipola are the selected back-row.
Mako Vunipola and Jack Willis are named among the replacements where Northampton lock David Ribbans could earn his first cap if he gets his shot from the bench.
“It’s been a really good week of preparation and I’ve been very pleased with the squad’s attitude,” Jones said.
“They’ve shown real work ethic and a determination to improve and our leaders, Owen, Ellis and Jack have really lifted the team.
“We’re looking forward to a great game of rugby at a full Twickenham Stadium against a very good Argentina side. It’s been a tough time for rugby lately and we hope that these autumn games show just what a special game it is.”
England XV to face Argentina:
Freddie Steward, Jack Nowell, Manu Tuilagi, Owen Farrell (captain), Joe Cokanasiga, Marcus Smith, Ben Youngs; Ellis Genge, Luke Cowan-Dickie, Kyle Sinckler, Alex Coles, Jonny Hill, Maro Itoje, Tom Curry, Billy Vunipola.
Replacements: Jack Singleton, Mako Vunipola, Joe Heyes, David Ribbans, Sam Simmonds, Jack Willis, Jack van Poortvliet, Henry Slade.